Biostatistics Unit
The Biostatistics Unit promotes rigorous, efficient and quality biomedical research, providing methodological and statistical advice throughout all stages of the research process: from formulating the question to the interpretation and dissemination of the results.
We offer support in the design of observational and interventional studies aimed at answering questions about diagnosis, treatment, and prognosis.
Our main services include:
- Methodological advice and study design.
- Sample size calculation.
- Database design and structuring.
- Data quality review and cleaning.
- Planning and carrying out the statistical analysis.
- Interpretation, presentation and communication of the results.
- Methodological support for systematic reviews.
- Critical appraisal of scientific papers.
Our aim is to collaborate closely with research teams to translate their questions into robust studies and their data into reliable, understandable and useful results for clinical practice and the generation of knowledge.
- Responsible: Dr. Ana Royuela Vicente
- Contact e-mail: aroyuela@idiphim.org
- Contact telephone: 91 191 75 53
Study design and planning
- Design of diagnostic, treatment and prognosis studies.
- Advice on observational and intervention studies.
- Sample size estimation.
- Preparation of the statistical analysis plan.
- Design and structuring of databases for data collection.
- Methodological advice on systematic reviews.
Statistical analysis
- Data debugging and quality control.
- Descriptive analysis and hypothesis testing.
- Evaluation of the validity and reproducibility of diagnostic tests.
- multivariable regression models: linear, logistic, survival
- Longitudinal data analysis. Mixed models. Multilevel models
- Advanced analytical techniques: propensity score, multiple imputation of missing data, crossover analysis, trend analysis (joinpoint).
- Development, evaluation and validation of predictive models.
Interpretation and dissemination of results
- Interpretation and presentation of the results.
- Methodological and statistical support for the preparation of:
- Scientific papers.
- Conference papers and posters.
- Research project reports.
- Doctoral theses.
- Support during the peer review process, including the preparation of responses to reviewers.
Training
- Critical appraisal of scientific papers.
- Applied Statistics for Health Sciences.
- Research methodology.
| SERVICIO | INTERNO | Public entity | Private non-profit entity | Private for-profit entity |
| Basic Biostatistics Service – Design of data collection files – Sample size estimation for simple designs – Results analysis: Descriptive analysis and hypothesis testing; Generation of charts and tables | Free* | 30 € | 45 € | 75 € |
| Advanced Biostatistics Service: – Design of research studies: diagnostic, treatment and prognostic studies – Design of the results analysis phase. – Results analysis: Regression models; Model validation. – Validity and reproducibility of diagnostic tests – Systematic reviews· Training: Critical Appraisal Skills for scientific articles; Statistics applied to Health Sciences Research methodology | Free* | 100 € | 150 € | 250 € |
(*) Funded projects will have a budget allocated for Biostatistics