INMUNIDAD Y LINFOPROLIFERATIVOS

Área: INMUNOLOGÍA Y GENÉTICA

Tipo de Grupo: Emergente

Jefe de Grupo: Gómez Lozano, Natalia

Principales Indicadores

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Proyectos competitivos
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Proyectos Europeos
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Publicaciones 2019
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Factor de Impacto

Miembros del grupo:

  • Krsnik Castello, Isabel
  • Navarro Matilla, Belén
  • Santos López, Adrián

La línea de investigación se centra en la identificación de factores inmunológicos e inmunogenéticos asociados a la variabilidad de las manifestaciones clínicas del virus de Epstein Barr (VEB) y su capacidad oncogénica, así como a otros herpesvirus.


1. Estudio del papel de la variabilidad en la respuesta inmune al VEB en síndromes linfoproliferativos y otras patologías asociadas al virus
2. Estudio de dianas para la prevención e inmunoterapia de infecciones por CMV

  • Exp: PI17/00298. Agencia Financiadora: INSTITUTO DE SALUD CARLOS III. IP: PALOMA MARTIN ACOSTA. Título: Papel de las células NK intratumorales y del eje CD94/NKG2A-HLA-E como herramienta inmunoterapeútica y de diagnóstico en el linfoma de Hodgkin asociado al virus de Epstein-Barr

  1. Paiva, Bruno, Puig, Noemi, Cedena, Maria-Teresa, Rosiñol, Laura, Cordón, Lourdes, Vidriales, María-Belén, Burgos, Leire, Flores-Montero, Juan, Sanoja-Flores, Luzalba, Lopez-Anglada, Lucia, Maldonado, Roberto, de la Cruz, Javier, Gutierrez, Norma C, Calasanz, Maria-Jose, Martin-Ramos, Maria-Luisa, Garcia-Sanz, Ramón, Martinez-Lopez, Joaquin, Oriol, Albert, Blanchard, María-Jesús, Rios, Rafael, Martin, Jesus, Martinez-Martinez, Rafael, Sureda, Anna, Hernandez, Miguel-Teodoro, de la Rubia, Javier, KRSNIK CASTELLO, ISABEL, Moraleda, Jose-Maria, Palomera, Luis, Bargay, Joan, Van Dongen, Jacques J M, Orfao, Alberto, Mateos, Maria-Victoria, Blade, Joan, San-Miguel, Jesús F, Lahuerta, Juan-José, GEM (Grupo Español de Mieloma)/PETHEMA (Programa Para el Estudio de la TerapéutiMeasurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma. Journal Of Clinical Oncology. 2019: – FI: FI:32,956(Q1)
  2. Bastidas, Adriana, de la Serna, Javier, El Idrissi, Mohamed, Oostvogels, Lidia, Quittet, Philippe, Lopez-Jimenez, Javier, Vural, Filiz, Pohlreich, David, Zuckerman, Tsila, Issa, Nicolas C., Gaidano, Gianluca, Lee, Je-Jung, Abhyankar, Sunil, Solano, Carlos, Perez de Oteyza, Jaime, Satlin, Michael J., Schwartz, Stefan, Campins, Magda, Rocci, Alberto, Llamas, Carlos Vallejo, Lee, Dong-Gun, Tan, Sen Mui, Johnston, Anna M., Grigg, Andrew, Boeckh, Michael J., Campora, Laura, Lopez-Fauqued, Marta, Heineman, Thomas C., Stadtmauer, Edward A., Sullivan, Keith M., Alonso Alonso, Aranzazu, Anagnostopoulos, Achilles, Andreadis, Charalambos (Babis), Angelopoulou, Maria, Anttila, Veli-Jukka, Aoun, Mickael, Barista, Ibrahim, Berkahn, Leanne, Bloor, Adrian J. C., Broady, Raewyn, Brossart, Peter, Buadi, Fra. et alEffect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation A Randomized Clinical Trial Jama-Journal Of The American Medical Association. 20192: 133-123 FI: FI:45,54(Q1)
  3. Rosinol, Laura, Oriol, Albert, Rios, Rafael, Sureda, Anna, Jesus Blanchard, Maria, Teodoro Hernandez, Miguel, Martinez-Martinez, Rafael, Moraleda, Jose M., Jarque, Isidro, Bargay, Juan, Gironella, Mercedes, de Arriba, Felipe, Palomera, Luis, Gonzalez-Montes, Yolanda, Marti, Josep M., KRSNIK CASTELLO, ISABEL, Arguinano, Jose M., Esther Gonzalez, Maria, Pilar Gonzalez, Ana, Felipe Casado, Luis, Lopez-Anglada, Lucia, Paiva, Bruno, Mateos, Maria-Victoria, San Miguel, Jesus F., Lahuerta, Juan-Jose, Blade, JoanBortezomib, lenalidomide, and dexamethasone as induction therapy prior to autologous transplant in multiple myeloma Blood. 201916: 1345-1337 FI: FI:17,543(Q1)
  4. MOÑIVAS PALOMERO, VANESA BELEN, Durante-Lopez, Alejandro, Torres Sanabria, Mario, SEGOVIA CUBERO, JAVIER, GONZALEZ MIRELIS, JESUS, VAZQUEZ LOPEZ-IBOR, JORGE, Navarro Rico, Sara M., KRSNIK CASTELLO, ISABEL, DOMINGUEZ RODRIGUEZ, FERNANDO, Martinez Mingo, Alejandro, HERNANDEZ PEREZ, FRANCISCO JOSE, CAVERO GIBAN, MIGUEL ANGEL, MINGO SANTOS, SUSANARole of Right Ventricular Strain Measured by Two-Dimensional Echocardiography in the Diagnosis of Cardiac Amyloidosis Journal Of The American Society Of Echocardiography. 20197: 845-845 FI: FI:5,508(Q1)
  5. Dagnew, Alemnew F, Ilhan, Osman, Lee, Won-Sik, Woszczyk, Dariusz, Kwak, Jae-Yong, Bowcock, Stella, Sohn, Sang Kyun, Rodriguez Macías, Gabriela, Chiou, Tzeon-Jye, Quiel, Dimas, Aoun, Mickael, NAVARRO MATILLA, BELEN, de la Serna, Javier, Milliken, Samuel, Murphy, John, McNeil, Shelly A, Salaun, Bruno, Di Paolo, Emmanuel, Campora, Laura, López-Fauqued, Marta, El Idrissi, Mohamed, Schuind, Anne, Heineman, Thomas C, Van den Steen, Peter, Oostvogels, Lidia, Zoster-039 study group, Acar, Kadir, Afanasyev, Boris, Alonso Alonso, Aránzazu, Anttila, Veli-Jukka, Barba Suñol, Pere, Blesing, Norbert, Comeau, Terrance, Del Campo, Teresa, Disperati, Patricia, Eek, Richard, Eom, HyeonSeok, Gaidano, Gianluca, Grosicki, Sebastian, Guillaume, Thierry, Homenda, Wojciech, Hwang, William, Ilyin, Nikolay, Johnsto. et alImmunogenicity and safety of the adjuvanted recombinant zoster vaccine in adults with haematological malignancies: a phase 3, randomised, clinical trial and post-hoc efficacy analysis. Lancet Infectious Diseases. 20199: 1000-988 FI: FI:24,446(Q1)
  6. Sobas, Marta, Montesinos, Pau, Boluda, Blanca, Bernal, Teresa, Vellenga, Edo, Nomdedeu, Josep, González-Campos, Jose, Chillón, Maria, Holowiecka, Aleksandra, Esteve, Jordi, Bergua, Juan, González-Sanmiguel, José David, Gil-Cortes, Cristina, Tormo, Mar, Salamero, Olga, Manso, Felix, Fernández, Isolda, de la Serna, Javier, Moreno, María-José, Pérez-Encinas, Manuel, KRSNIK CASTELLO, ISABEL, Ribera, Josep-Maria, Escoda, Lourdes, Lowenberg, Bob, Sanz, Miguel Angel, PETHEMA, HOVON, PALG, and GATLA cooperative groupsAn analysis of the impact of CD56 expression in de novo acute promyelocytic leukemia patients treated with upfront all-trans retinoic acid and anthracycline-based regimens. Leukemia & Lymphoma. 20194: 6-1 FI: FI:2,969(Q3)
  7. Lahuerta, Juan-José, Jiménez-Ubieto, Ana, Paiva, Bruno, Martínez-López, Joaquín, González-Medina, José, López-Anglada, Lucía, Cedena, María-Teresa, Puig, Noemi, Oriol, Albert, Blanchard, María-Jesús, Ríos, Rafael, Martin, Jesús, Martínez, Rafael, Sureda, Anna, Hernández, Miguel Teodoro, de la Rubia, Javier, KRSNIK CASTELLO, ISABEL, Cabañas, Valentín, Palomera, Luis, Bargay, Joan, Mateos, María-Victoria, Rosiñol, Laura, San Miguel, Jesús F, Blade, JoanRole of urine immunofixation in the complete response assessment of MM patients other than light-chain-only disease. Blood. 201925: 2668-2664 FI: FI:17,543(Q1)
  8. Puig, Noemi, Paiva, Bruno, Lasa, Marta, Burgos, Leire, Perez, Jose J, Merino, Juana, Moreno, Cristina, Vidriales, Maria-Belen, Toboso, Dolores Gómez, Cedena, Maria-Teresa, Ocio, Enrique M, Lecumberri, Ramon, García de Coca, Alfonso, Labrador, Jorge, Gonzalez, Maria-Esther, Palomera, Luis, Gironella, Mercedes, Cabañas, Valentin, Casanova, Maria, Oriol, Albert, KRSNIK CASTELLO, ISABEL, Pérez-Montaña, Albert, de la Rubia, Javier, de la Puerta, Jose-Enrique, de Arriba, Felipe, Prosper, Felipe, Martinez-Lopez, Joaquin, Lecrevisse, Quentin, Verde, Javier, Mateos, Maria-Victoria, Lahuerta, Juan-Jose, Orfao, Alberto, San Miguel, Jesús FFlow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis. Leukemia. 20195: 1267-1256 FI: FI:8,665(Q1)
  9. Lopez-Corral, Lucia, Caballero-Velazquez, Teresa, Lopez-Godino, Oriana, Rosinol, Laura, Perez-Vicente, Sabina, Fernandez-Aviles, Francesc, KRSNIK CASTELLO, ISABEL, MORILLO GILES, DANIEL, Heras, Inmaculada, Morgades, Mireia, Rifon, Jose J., Sampol, Antonia, Iniesta, Francisca, Ocio, Enrique-Maria, Martin, Jesus, Rovira, Montserrat, CABERO BECERRA, MARTIN ANTONIO, Castilla-Llorente, Cristina, Ribera, Josep-Maria, Torres-Juan, Marta, Maria Moraleda, Jose, Martinez, Carmen, Vazquez, Alejandro, Gutierrez, Gonzalo, Caballero, Dolores, San Miguel, Jesus F., Mateos, Maria-Victoria, Antonio Perez-Simon, JoseResponse to Novel Drugs before and after Allogeneic Stem Cell Transplantation in Patients with Relapsed Multiple Myeloma Biology Of Blood And Marrow Transplantation. 20199: 1712-1703 FI: FI:3,853(Q2)
  10. ZEGRI REIRIZ, ISABEL, DE HARO DEL MORAL, FRANCISCO JAVIER, DOMINGUEZ RODRIGUEZ, FERNANDO, SALAS ANTON, CLARA, DE LA CUADRA VIRGILI, PABLO, PLAZA LOPEZ, ARESIO, KRSNIK CASTELLO, ISABEL, GONZALEZ LOPEZ, ESTHER, GARCIA PAVIA, PABLOPrevalence of Cardiac Amyloidosis in Patients with Carpal Tunnel Syndrome Journal Of Cardiovascular Translational Research. 20196: 513-507 FI: FI:3,312(Q2)
  11. Salamero, Olga, Martinez-Cuadron, David, Sobas, Marta, Benavente, Celina, Vives, Susana, De la Serna, Javier, Perez-Encinas, Manuel, Escoda, Lourdes, Gil, Cristina, Brunet, Salut, Ramos, Fernando, Esteve, Jordi, Amigo, Mariluz, KRSNIK CASTELLO, ISABEL, Manso, Felix, Arias, Jesus, Gonzalez-Campos, Jose, Serrano, Josefina, Oleksiuk, Jalanta, Barrios, Manuel, Garcia-Boyero, Raimundo, Novo, Andres, Sanz, Miguel A., Montesinos, Pau, Helbig, G., Holowiecka, A., Armatys, A., Hawrylecka, D., Golos, A., Ejduk, A., Majcherek, M., Skret, A., Czyzewska, J., Grosicki, S., Zarzycka, E., Watek, M., Piatkowska-Jakubas, B., Holojda, J., Pluta, A., Podhorecka, M., Gromek, T., Guzicka, E., Charlinski, G., Paluszewska, M., Beltran de Heredia, J. M., Hernandez, J. M., Arias, J., Ramos, F., Roman, A., de la Ser. et alReal life outcomes of patients aged >= 75 years old with acute promyelocytic leukemia: experience of the PETHEMA registry Leukemia & Lymphoma. 201911: 2732-2720 FI: FI:2,969(Q3)
  12. Labrador, Jorge, Luño, Elisa, Vellenga, Edo, Brunet, Salut, González-Campos, José, Chillón, Maria C, Holowiecka, Aleksandra, Esteve, Jordi, Bergua, Juan, González-Sanmiguel, José D, Gil, Cristina, Tormo, Mar, Salamero, Olga, Manso, Felix, Fernández, Isolda, de laSerna, Javier, Moreno, María-José, Pérez-Encinas, Manuel, KRSNIK CASTELLO, ISABEL, Ribera, Josep-Maria, Cervera, Jose, Calasanz, María J, Boluda, Blanca, Sobas, Marta, Lowenberg, Bob, Sanz, Miguel A, Montesinos, PauClinical significance of complex karyotype at diagnosis in pediatric and adult patients with de novo acute promyelocytic leukemia treated with ATRA and chemotherapy. Leukemia & Lymphoma. 20195: 10-1 FI: FI:2,969(Q3)
  13. LOPEZ SAINZ, ANGELA, DE HARO DEL MORAL, FRANCISCO JAVIER, DOMINGUEZ RODRIGUEZ, FERNANDO, RESTREPO CORDOBA, MARIA ALEJANDRA, Amor-Salamanca, Almudena, Hernandez-Hernandez, Aitor, Ruiz-Guerrero, Luis, KRSNIK CASTELLO, ISABEL, COBO MARCOS, MARTA, CASTRO URDA, VICTOR, TOQUERO RAMOS, JORGE, Lara-Pezzi, Enrique, FERNANDEZ LOZANO, IGNACIO, ALONSO-PULPON RIVERA, LUIS, GONZALEZ LOPEZ, ESTHER, GARCIA PAVIA, PABLOPrevalence of cardiac amyloidosis among elderly patients with systolic heart failure or conduction disorders Amyloid-Journal Of Protein Folding Disorders. 20193: 163-156 FI: FI:4,323(Q2)
  14. Curran, Desmond, Matthews, Sean, Rowley, Scott D, Young, Jo-Anne H, Bastidas, Adriana, Anagnostopoulos, Achilles, Barista, Ibrahim, Chandrasekar, Pranatharthi Haran, Dickinson, Michael, El Idrissi, Mohamed, Heras, Inmaculada, Milliken, Samuel T, Monserrat Coll, Jorge, NAVARRO MATILLA, BELEN, Oostvogels, Lidia, Piatkowska-Jakubas, Beata, Quiel, Dimas, Sabry, Waleed, Schwartz, Stefan, Selleslag, Dominik L D, Sullivan, Keith M, Theunissen, Koen, Yegin, Zeynep Arzu, Yeh, Su-Peng, Zaja, Francesco, Szer, Jeff, ZOE-HSCT Study group collaboratorsRecombinant Zoster Vaccine Significantly Reduces the Impact on Quality of Life Caused by Herpes Zoster in Adult Autologous Hematopoietic Stem Cell Transplant Recipients: A Randomized Placebo-Controlled Trial (ZOE-HSCT). Biology Of Blood And Marrow Transplantation. 201912: 2481-2474 FI: FI:3,853(Q2)