ENFERMEDAD INFLAMATORIA INTESTINAL

Área: BIOPATOLOGÍA CARDIOVASCULAR, DIGESTIVAS Y REUMATOLOGÓGICA

Tipo de Grupo: Investigación Clínica

Jefe de Grupo: Vera Mendoza, María Isabel

Principales Indicadores

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Proyectos competitivos
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Proyectos Europeos
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Publicaciones 2020
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Factor de Impacto

Miembros del grupo:

  • Calvo Moya, Marta Isabel
  • González Lama, Yago
  • González Partida, Irene
  • Matallana Royo, Virginia

La actividad desarrollada por el grupo de Enfermedad Inflamatoria Intestinal se centra en la investigación principalmente de carácter clínico, con alguna aportación de carácter básico, de manera individual y en colaboración con otros grupos de trabajo de este campo como el grupo nacional de enfermedad de Crohn y colitis ulcerosa (GETECCU).

En la actualidad estamos iniciando una línea de investigación en big data a nivel de la Comunidad de Madrid, en desarrollo con otros hospitales, para establecer patrones pronósticos de enfermedad y de respuesta terapéutica.

1. Eficacia y seguridad de nuevas moléculas terapéuticas (ensayos multicéntricos internacionales)
2. Endoscopia en la enfermedad inflamatoria intestinal
3. Telemedicina en la enfermedad inflamatoria intestinal
4. Big data en enfermedad inflamatoria intestinal
5. Detección precoz de enfermedad inflamatoria intestinal en pacientes con patología reumatológica

  • Exp: 40100203. Agencia Financiadora: Merck Sharp & Dohme de España. IP: MARIA ISABEL VERA MENDOZA. Título: CONVENIO DE COLABORACIÓN EN ACTIVIDADES DE INTERES GENERAL 2019
  • Exp: 40100216. Agencia Financiadora: Merck Sharp & Dohme de España. IP: MARIA ISABEL VERA MENDOZA. Título: CONVENIO DE COLABORACIÓN EN ACTIVIDADES DE INTERES GENERAL 2020

  1. El Hajra Martinez, Ismael , Relea Perez, Lucia , CALVO MOYA, MARTA ISABELPresence of SARS-Coronavirus-2 in the Ileal Mucosa: Another Evidence for Infection of GI Tract by This Virus Gastroenterology. 2020159(4): 1624-1624 FI: FI:22,682(Q1)
  2. Shen, Bo , Kochhar, Gursimran , Navaneethan, Udayakumar , Farraye, Francis A. , Schwartz, David A. , Iacucci, Marietta , Bernstein, Charles N. , Dryden, Gerald , Cross, Raymond , Bruining, David H. , Kobayashi, Taku , Lukas, Martin , Shergill, Amandeep , Bortlik, Martin , Lan, Nan , Lukas, Milan , Tang, Shou-Jiang , Kotze, Paulo Gustavo , Kiran, Ravi P. , Dulai, Parambir S. , El-Hachem, Sandra , Coelho-Prabhu, Nayantara , Thakkar, Shyam , Mao, Ren , Chen, Guodong , Zhang, Shengyu , Gonzalez Suarez, Begona , GONZALEZ LAMA, YAGO, Silverberg, Mark S. , Sandborn, William J. Practical guidelines on endoscopic treatment for Crohn’s disease strictures: a consensus statement from the Global Interventional Inflammatory Bowel Disease Group Lancet Gastroenterology & Hepatology. 20205(4): 405-393 FI: FI:18,486(Q1)
  3. Rodríguez de Santiago, Enrique , Shimamura, Yuto , Pioche, Mathieu , Eleftheriadis, Nikos , Albéniz, Eduardo , Bechara, Robert , Yan Chiu, Philip Way , Guarner-Argente, Carlos , HERREROS DE TEJADA ECHANOJAUREGUI, ALBERTO, Uchima, Hugo , Fujiyoshi, Yusuke , Ponchon, Thierry , González-Gete, Gonzalo , Hew, Simon , Murzi-Pulgar, Marianette , MATALLANA ROYO, VIRGINIA, Parejo-Carbonell, Sofía , Estremera-Arévalo, Fermín , Moll, Frederic , Onimaru, Manabu , Inoue, Haruhiro Safety and effectiveness of peroral endoscopic myotomy in patients on antiplatelet or anticoagulant therapy: an international multicenter case-control study. Gastrointestinal Endoscopy. 2020 FI: FI:9,427(Q)
  4. Charbit-Henrion, Fabienne , Parlato, Marianna , Hanein, Sylvain , Duclaux-Loras, Rémi , Nowak, Jan , Begue, Bernadette , Rakotobe, Sabine , Bruneau, Julie , Fourrage, Cécile , Alibeu, Olivier , Rieux-Laucat, Frédéric , Lévy, Eva , Stolzenberg, Marie-Claude , Mazerolles, Fabienne , Latour, Sylvain , Lenoir, Christelle , Fischer, Alain , Picard, Capucine , Aloi, Marina , Dias, Jorge Amil , Hariz, Mongi Ben , Bourrier, Anne , Breuer, Christian , Breton, Anne , Bronsky, Jiri , Buderus, Stephan , Cananzi, Mara , Coopman, Stéphanie , Crémilleux, Clara , Dabadie, Alain , Dumant-Forest, Clémentine , Gurkan, Odul Egritas , Fabre, Alexandre , Fischer, Aude , Diaz, Marta German , GONZALEZ LAMA, YAGO, Goulet, Olivier , Guariso, Graziella , Gurcan, Neslihan , Homan, Matjaz , Hugot, Jean-Pierre , Jezior. et alCorrigendum to: Diagnostic Yield of Next-Generation Sequencing in Very Early-Onset Inflammatory Bowel Diseases: A Multicenter Study. Journal Of Crohns & Colitis. 2020 FI: FI:9,071(Q)
  5. Calafat, Margalida , Manosa, Miriam , Mesonero, Francisco , Guardiola, Jordi , Minguez, Miguel , Nos, Pilar , VERA MENDOZA, MARIA ISABEL, Taxonera, Carlos , Iglesias, Eva , Ricart, Elena , Gisbert, Javier P. , Calvet, Xavier , Garcia-Lopez, Santiago , Monfort, David , Perez Calle, Jose Lazaro , Riestra, Sabino , Gomollon, Fernando , Garcia-Planella, Esther , Bermejo, Fernando , Hernandez, Vicent , Dolores Martin-Arranz, Maria , Gutierrez, Ana , Torres, Paola , Canete, Fiorella , Domenech, Eugeni , ENEIDA Registry GETECCU Switching to a Second Thiopurine in Adult and Elderly Patients With Inflammatory Bowel Disease: A Nationwide Study From the ENEIDA Registry Journal Of Crohns & Colitis. 202014(9): 1298-1290 FI: FI:9,071(Q1)
  6. Eliadou, Elena , Moleiro, Joana , Ribaldone, Davide Giuseppe , Astegiano, Marco , Rothfuss, Katja , Taxonera, Carlos , Ghalim, Fahd , Carbonnel, Franck , Verstockt, Bram , Festa, Stefano , Maia, Luís , Berrozpe, Ana , Zagorowicz, Edyta , Savarino, Edoardo , Ellul, Pierre , Vavricka, Stephan R , CALVO MOYA, MARTA ISABEL, Koutroubakis, Ioannis , Hoentjen, Frank , Luis, Fernández Salazar , Callela, Francesca , Cañete Pizarro, Fiorella , Soufleris, Konstantinos , Sonnenberg, Elena , Cavicchi, Maryan , Wypych, Joanna , Hommel, Christophe , Ghiani, Alessandro , Fiorino, Gionata , ECCO CONFER COMMITTEE Interstitial and Granulomatous lung disease in inflammatory bowel disease patients. Journal Of Crohns & Colitis. 202014(4): 489-480 FI: FI:9,071(Q1)
  7. Rodriguez-Lago, Iago , Castro-Poceiro, Jesus , Fernandez-Clotet, Agnes , Mesonero, Francisco , Lopez-Sanroman, Antonio , Lopez-Garcia, Alicia , Marquez, Lucia , Clos-Parals, Ariadna , Canete, Fiorella , Vicuna, Miren , Nantes, Oscar , Merino, Olga , MATALLANA ROYO, VIRGINIA, Gordillo, Jordi , Elorza, Ainara , Vicente, Raquel , Jose Casanova, Maria , Ferreiro-Iglesias, Rocio , Perez-Galindo, Pablo , Manuel Benitez, Jose , Taxonera, Carlos , Jose Garcia, Maria , Martin, Eduardo , Aguirre, Urko , Gisbert, Javier P. , Young GETECCU Grp Tacrolimus induces short-term but not long-term clinical response in inflammatory bowel disease Alimentary Pharmacology & Therapeutics. 202051(9): 879-870 FI: FI:8,171(Q1)
  8. Kopylov, Uri , Hanzel, Jurij , Liefferinckx, Claire , De Marco, Davide , Imperatore, Nicola , Plevris, Nikolas , Baston-Rey, Iria , Harris, Richard J. , Truyens, Marie , Domislovic, Viktor , Vavricka, Stephan , Biemans, Vince , Myers, Sally , Sebastian, Shaji , Ben-Horin, Shomron , GONZALEZ LAMA, YAGO, Gilletta, Cyrielle , Ariella, Bar-Gil Shitrit , Zelinkova, Zuzana , Weishof, Roni , Storan, Darragh , Zittan, Eran , Farkas, Klaudia , Molnar, Tamas , Franchimont, Denis , Cremer, Anneline , Afif, Waqqas , Castiglione, Fabiana , Lees, Charles , Barreiro-de Acosta, Manuel , Lobaton, Triana , Doherty, Glen , Krznaric, Zeljko , Pierik, Marieke , Hoentjen, Frank , Drobne, David Effectiveness of ustekinumab dose escalation in Crohn’s disease patients with insufficient response to standard-dose subcutaneous maintenance therapy Alimentary Pharmacology & Therapeutics. 202052(1): 142-135 FI: FI:8,171(Q1)
  9. Calvet, Xavier , Saldaña, Roberto , Carpio, Daniel , Mínguez, Miguel , VERA MENDOZA, MARIA ISABEL, Juliá, Berta , Marín, Laura , Casellas, Fransesc Improving Quality of Care in Inflammatory Bowel Disease Through Patients’ Eyes: IQCARO Project. Inflammatory Bowel Diseases. 202026(5): 791-782 FI: FI:5,325(Q2)
  10. Casanova, María José , Chaparro, María , Mínguez, Miguel , Ricart, Elena , Taxonera, Carlos , García-López, Santiago , Guardiola, Jordi , López-San Román, Antonio , Iglesias, Eva , Beltrán, Belén , Sicilia, Beatriz , VERA MENDOZA, MARIA ISABEL, Hinojosa, Joaquín , Riestra, Sabino , Domènech, Eugeni , Calvet, Xavier , Pérez-Calle, José Lázaro , Martín-Arranz, María Dolores , Aldeguer, Xavier , Rivero, Montserrat , Monfort, David , Barrio, Jesús , Esteve, María , Márquez, Lucía , Lorente, Rufo , García-Planella, Esther , de Castro, Luisa , Bermejo, Fernando , Merino, Olga , Rodríguez-Pérez, Antonio , Martínez-Montiel, Pilar , Van Domselaar, Manuel , Alcaín, Guillermo , Domínguez-Cajal, Manuel , Muñoz, Carmen , Gomollón, Fernando , Fernández-Salazar, Luis , García-Sepulcre, Mariana Fe , Rodrí. et alEffectiveness and Safety of the Sequential Use of a Second and Third Anti-TNF Agent in Patients With Inflammatory Bowel Disease: Results From the Eneida Registry. Inflammatory Bowel Diseases. 202026(4): 616-606 FI: FI:5,325(Q2)
  11. Rodriguez-Lago, Iago , Hoyo, Javier Del , Perez-Girbes, Alexandre , Garrido-Marin, Alejandro , Casanova, Maria Jose , Chaparro, Maria , Fernandez-Clotet, Agnes , Castro-Poceiro, Jesus , Garcia, Maria Jose , Sanchez, Sara , Ferreiro-Iglesias, Rocio , Baston, Iria , Piqueras, Marta , Careda, Lola Esteba i Bech de Careda , Mena, Raquel , Suarez, Cristina , Cordon, Joaquin Poza , Lopez-Garcia, Alicia , Marquez, Lucia , Arroyo, Maite , Alfambra, Erika , Sierra, Monica , Cano, Noelia , Delgado-Guillena, Pedro , Morales-Alvarado, Victor , Aparicio, Juan Carlos , Guerra, Ivan , Aullo, Carolina , Merino, Olga , Arranz, Laura , Hidalgo, Maria Araceli , Llao, Jordina , Plaza, Rocio , Molina, Gema , Torres, Paola , Perez-Galindo, Pablo , Romero, Maria Giselle , Herrera-deGuise, Claudia , Armesto, Edis. et alEarly treatment with anti-tumor necrosis factor agents improves long-term effectiveness in symptomatic stricturing Crohn’s disease United European Gastroenterology Journal. 20208(9): 1066-1056 FI: FI:4,623(Q2)
  12. Iborra, Marisa , Garcia-Morales, Natalia , Rubio, Saoia , Bertoletti, Federico , CALVO MOYA, MARTA ISABEL, Taxonera, Carlos , Bosca-Watts, Marta Maia , Sierra, Monica , Mancenido, Noemi , Beltran, Belen , Castillejo, Oscar Nantes , Garcia-Planella, Esther , VERA MENDOZA, MARIA ISABEL, Alba, Cristina , Marti-Aguado, David , Ballester, Maria Pilar , Cano-Sanz, Noelia , Pajares-Villarroya, Ramon , Cerrillo, Elena , Canada, Antonio , Nos, Pilar Real-life experience with 4 years of golimumab persistence in ulcerative colitis patients Scientific Reports. 202010(1): 17774-17774 FI: FI:4,379(Q1)
  13. Guasch, Montserrat , Canete, Fiorella , Ordas, Ingrid , Iglesias-Flores, Eva , Clos, Ariadna , Gisbert, Javier P. , Taxonera, Carlos , VERA MENDOZA, MARIA ISABEL, Minguez, Miguel , Guardiola, Jordi , Rivero, Montserrat , Nos, Pilar , Gomollon, Fernando , Barrio, Jesus , de Francisco, Ruth , Lopez-Sanroman, Antonio , Dolores Martin-Arranz, M. , Garcia-Planella, Esther , Camargo, Raquel , Garcia-Lopez, Santiago , de Castro, Luisa , Calvet, Xavier , Esteve, Maria , Manosa, Miriam , Domenech, Eugeni , GETECCU-ENEIDA Registry Changes in the requirement for early surgery in inflammatory bowel disease in the era of biological agents Journal Of Gastroenterology And Hepatology. 202035(12): 2087-2080 FI: FI:4,029(Q2)
  14. RAMOS MARTINEZ, ANTONIO, Martinez-Ruiz, R. , MUÑEZ RUBIO, ELENA, Valencia-Alijo, A. , Ferre-Aracil, C. , VERA MENDOZA, MARIA ISABELEffect of faecal microbiota transplantation on recurrent urinary tract infection in a patient with long-term suprapubic urinary catheter Journal Of Hospital Infection. 2020105(2): 333-332 FI: FI:3,926(Q1)
  15. Echarri, Ana , VERA MENDOZA, MARIA ISABEL, Ollero, Virginia , Arajol, Claudia , Riestra, Sabino , Robledo, Pilar , CALVO MOYA, MARTA ISABEL, Gallego, Franscisco , Ceballos, Daniel , Castro, Beatriz , Aguas, Mariam , García-López, Santiago , Marín-Jiménez, Ignacio , Chaparro, María , Mesonero, Paco , Guerra, Iván , Guardiola, Jordi , Nos, Pilar , Muñiz, Javier The Harvey-Bradshaw Index Adapted to a Mobile Application Compared with In-Clinic Assessment: The MediCrohn Study. TELEMEDICINE AND E-HEALTH. 202026(1): 88-80 FI: FI:3,536(Q3)
  16. Casellas, Francesc , Guinard Vicens, Daniel , Garcia-Lopez, Santiago , GONZALEZ LAMA, YAGO, Arguelles-Arias, Federico , Barreiro-de Acosta, Manuel , Marin Sanchez, Laura , Manuel Mendive, Juan , Saldana, Roberto , Cabez, Ana , Gomez, Susana , Loza, Estibaliz Consensus document on the management preferences of patients with ulcerative colitis: points to consider and recommendations European Journal Of Gastroenterology & Hepatology. 202032(12): 1522-1514 FI: FI:2,566(Q4)
  17. Chaparro, Maria , Guerra, Ivan , Iborra, Marisa , Luis Cabriada, Jose , Bujanda, Luis , Taxonera, Carlos , Garcia-Sanchez, Valle , Marin-Jimenez, Ignacio , Barreiro-de Acosta, Manuel , VERA MENDOZA, MARIA ISABEL, Dolores Martin-Arranz, Maria , Hernandez-Breijo, Borja , Mesonero, Francisco , Sempere, Laura , Gomollon, Fernando , Hinojosa, Joaquin , Bermejo, Fernando , Beltran, Belen , Rodriguez Pescador, Ainhoa , Maria Banales, Jesus , Olivares, David , Aguilar-Melero, Patricia , Menchen, Luis , Ferreiro-Iglesias, Rocio , Blazquez Gomez, Isabel , Benitez Garcia, Belen , Gonzalez Guijarro, Luis , Marin, Alicia , Bernardo, David , Gisbert, Javier P. , PREDICROHN Study Grp GETECCU Usefulness of monitoring antitumor necrosis factor serum levels during the induction phase in patients with Crohn’s disease European Journal Of Gastroenterology & Hepatology. 202032(5): 596-588 FI: FI:2,566(Q4)
  18. Aguilar Del Rey, Javier , Jódar Gimeno, Esteban , Brañas Baztán, Fátima , Gómez Alonso, Carlos , GONZALEZ LAMA, YAGO, Malouf Sierra, Jorge , Borrego, Rafael Sánchez , Segura de la Morena, Julián , Suárez Pérez, Jorge Alonso , Valdés Y Llorca, Carmen Is vitamin-D supplementation not useful in patients at risk of fractures and falls? Gynecological Endocrinology. 202036(2): 3-1 FI: FI:2,26(Q3)
  19. Sicilia, Beatriz , Garcia-Lopez, Santiago , GONZALEZ LAMA, YAGO, Zabana, Yamile , Hinojosa, Joaquin , Gomollon, Fernando , Spanish Grp Working Crohn’s Dis Ul GETECCU 2020 guidelines for the treatment of ulcerative colitis. Developed using the GRADE approach Gastroenterologia y Hepatologia. 202043(1): 57-1 FI: FI:2,102(Q4)
  20. GONZALEZ LAMA, YAGO, SANZ SANZ, JESUS, Bastida, Guillermo , CAMPOS ESTEBAN, JOSE, Ferreiro, Rocio , Joven, Beatriz , Gutierrez, Ana , Juanola, Xavier , Sicilia, Beatriz , Veroz, Raul , Gisbert, Javier P. , Chaparro, Maria , Domenech, Eugeni , Esteve, Maria , Gomollon, Fernando Recommendations by the Spanish Working Group on Crohn’s Disease and Ulcerative Colitis (GETECCU) on the treatment of patients with inflammatory bowel disease associated with spondyloarthritis Gastroenterologia y Hepatologia. 202043(5): 283-273 FI: FI:2,102(Q4)
  21. Martínez-Lozano, Helena , Miranda-Bautista, José , GONZALEZ LAMA, YAGO, Carpio, Daniel , Barreiro-de Acosta, Manuel , Pérez-Calle, José L , Relea Pérez, Lucía , Villa, Keyla , MATALLANA ROYO, VIRGINIA, CALVO MOYA, MARTA ISABEL, VERA MENDOZA, MARIA ISABEL, Pérez Galindo, Pablo , Mora-Cuadrado, Natalia , Lopez-Serrano, Pilar , Marín-Jiménez, Ignacio , Menchén, Luis Comparison of original and biosimilar infliximab (CTP-13) in biologic-naïve patients with Crohn’s disease and ulcerative colitis: a retrospective, multicenter real-life study in Spain. Revista Espanola De Enfermedades Digestivas. 2020 FI: FI:2,086(Q4)
  22. Crespo, Javier , Carballo Alvarez, Fernando , Alberca, Fernando , Fernandez, Conrado , VERA MENDOZA, MARIA ISABEL, Gomez Ruiz, Marcos , Elola Somoza, Francisco Javier Digestive units in the National Health System of the 21st century. Organizational and management standards for a patient-centered service Revista Espanola De Enfermedades Digestivas. 2020112(2): 149-144 FI: FI:2,086(Q4)