ENFERMEDAD INFLAMATORIA INTESTINAL

Área: BIOPATOLOGÍA CARDIOVASCULAR, DIGESTIVAS Y REUMATOLOGÓGICA

Tipo de Grupo: Investigación Clínica

Jefe de Grupo: Vera Mendoza, María Isabel

Principales Indicadores

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Proyectos competitivos
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Proyectos Europeos
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Publicaciones 2019
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Factor de Impacto

Miembros del grupo:

  • Abreu García, Luis Esteban
  • Calvo Moya, Marta Isabel
  • González Lama, Yago
  • Matallana Royo, Virginia
La actividad desarrollada por el grupo de Enfermedad Inflamatoria Intestinal se centra en la investigación principalmente de carácter clínico, con alguna aportación de carácter básico, de manera individual y en colaboración con otros grupos de trabajo de este campo como el grupo nacional de enfermedad de Crohn y colitis ulcerosa (GETECCU).En la actualidad estamos iniciando una línea de investigación en big data a nivel de la Comunidad de Madrid, en desarrollo con otros hospitales, para establecer patrones pronósticos de enfermedad y de respuesta terapéutica.


1. Eficacia y seguridad de nuevas moléculas terapéuticas (ensayos multicéntricos internacionales)
2. Endoscopia en la enfermedad inflamatoria intestinal
3. Telemedicina en la enfermedad inflamatoria intestinal
4. Big data en enfermedad inflamatoria intestinal
5. Detección precoz de enfermedad inflamatoria intestinal en pacientes con patología reumatológica

  1. Hedin, C R H, Vavricka, S R, Stagg, A, Schoepfer, A, Raine, T, Puig, L, Pleyer, U, Navarini, A, van der Meulen, A, Maul, J, Katsanos, K, Kagramanova, A, Greuter, T, GONZALEZ LAMA, YAGO, van Gaalen, F, Ellul, P, Burisch, J, Bettenworth, D, Becker, M D, Bamias, G, Rieder, FThe Pathogenesis of Extraintestinal Manifestations: Implications for IBD research, diagnosis and therapy. Journal Of Crohns & Colitis. 20195: 554-541 FI: FI:8,658(Q1)
  2. Calafat, Margalida, Manosa, Miriam, Canete, Fiorella, Ricart, Elena, Iglesias, Eva, CALVO MOYA, MARTA ISABEL, Rodriguez-Moranta, Francisco, Taxonera, Carlos, Nos, Pilar, Mesonero, Francisco, Martin-Arranz, Maria-Dolores, Minguez, Miguel, Gisbert, Javier P., Garcia-Lopez, Santiago, de Francisco, Ruth, Gomollon, Fernando, Calvet, Xavier, Garcia-Planella, Esther, Rivero, Montserrat, Martinez-Cadilla, Jesus, Arguelles, Federico, Arias, Lara, Cimavilla, Marta, Zabana, Yamile, Domenech, Eugeni, Abad, Agueda, Alcain, Guillermo, Almela, Pedro, Barreiro-de-Acosta, Manuel, Ber, Yolanda, Bermejo, Fernando, Bujanda, Luis, Busquets, David, Charro, Mara, Garcia-Bosch, Orlando, Garcia-Sepulcre, Mariana-Fe, Gutierrez, Ana, Khorrami, Sam, Lazaro, Jose, Legido, Jesus, Liao, Jordina, Lucendo, Alfredo J., Mad. et alIncreased risk of thiopurine-related adverse events in elderly patients with IBD Alimentary Pharmacology & Therapeutics. 20197: 788-780 FI: FI:7,515(Q1)
  3. Casanova, María José, Chaparro, María, Mínguez, Miguel, Ricart, Elena, Taxonera, Carlos, García-López, Santiago, Guardiola, Jordi, López-San Román, Antonio, Iglesias, Eva, Beltrán, Belén, Sicilia, Beatriz, VERA MENDOZA, MARIA ISABEL, Hinojosa, Joaquín, Riestra, Sabino, Domènech, Eugeni, Calvet, Xavier, Pérez-Calle, José Lázaro, Martín-Arranz, María Dolores, Aldeguer, Xavier, Rivero, Montserrat, Monfort, David, Barrio, Jesús, Esteve, María, Márquez, Lucía, Lorente, Rufo, García-Planella, Esther, de Castro, Luisa, Bermejo, Fernando, Merino, Olga, Rodríguez-Pérez, Antonio, Martínez-Montiel, Pilar, Van Domselaar, Manuel, Alcaín, Guillermo, Domínguez-Cajal, Manuel, Muñoz, Carmen, Gomollón, Fernando, Fernández-Salazar, Luis, García-Sepulcre, Mariana Fe, Rodríguez-Lago, Iago, Gutiérrez, Ana, Argü. et alEffectiveness and Safety of the Sequential Use of a Second and Third Anti-TNF Agent in Patients With Inflammatory Bowel Disease: Results From the Eneida Registry. Inflammatory Bowel Diseases. 2019: – FI: FI:4,261(Q2)
  4. Adler, Samuel N., GONZALEZ LAMA, YAGO, MATALLANA ROYO, VIRGINIA, SUAREZ FERRER, CRISTINA JULIA, Schwartz, Avraham, Shitrit, Ariella Bar-GilComparison of small-bowel colon capsule endoscopy system to conventional colonoscopy for the evaluation of ulcerative colitis activity Endoscopy International Open. 201910: 1261-1253 FI: FI:0(Q)
  5. Chaparro, María, Barreiro-de Acosta, Manuel, Echarri, Ana, Almendros, Rosendo, Barrio, Jesús, Llao, Jordina, Gomollón, Fernando, VERA MENDOZA, MARIA ISABEL, Cabriada, José Luis, Guardiola, Jordi, Guerra, Iván, Beltrán, Belén, Roncero, Oscar, Busquets, David, Taxonera, Carlos, Calvet, Xavier, Ferreiro-Iglesias, Rocío, Ollero Pena, Virginia, Bernardo, David, Donday, María G, Garre, Ana, Godino, Ana, Díaz, Ana, Gisbert, Javier PCorrelation Between Anti-TNF Serum Levels and Endoscopic Inflammation in Inflammatory Bowel Disease Patients. Digestive Diseases And Sciences. 20193: 854-846 FI: FI:2,751(Q3)
  6. Aterido, Adria, Palau, Nuria, Domenech, Eugeni, Nos Mateu, Pilar, Gutierrez, Ana, Gomollon, Fernando, Mendoza, Juan L., Garcia-Planella, Esther, Barreiro-de Acosta, Manuel, Munoz, Fernando, VERA MENDOZA, MARIA ISABEL, Saro, Cristina, Esteve, Maria, Andreu, Montserrat, Chaparro, Maria, Panes, Julian, Garcia-Sanchez, Valle, Lopez-Lasanta, Maria, Pluma, Andrea, Codo, Laia, Garcia-Montero, Andres, Manye, Josep, Gisbert, Javier P., Marsal, Sara, Julia, AntonioGenetic association between CD96 locus and immunogenicity to anti-TNF therapy in Crohn’s disease Pharmacogenomics Journal. 20196: 555-547 FI: FI:2,91(Q2)
  7. Taxonera, Carlos, Lopez-Sanroman, Antonio, VERA MENDOZA, MARIA ISABEL, Domenech, Eugeni, Vega Ruiz, Vicente, Marin-Jimenez, Ignacio, Guardiola, Jordi, Castro, Luisa, Esteve, Maria, Iglesias, Eva, Ceballos, Daniel, Martinez-Montiel, Pilar, Gisbert, Javier P., Minguez, Miguel, Echarri, Ana, Calvet, Xavier, Barrio, Jesus, Hinojosa, Joaquin, Dolores Martin-Arranz, Maria, Marquez-Mosquera, Lucia, Bermejo, Fernando, Rimola, Jordi, Alba, Cristina, Pons, Vicente, Nos, Pilar, Spanish GETECCU Grp APPRECIA StudyQuality of life during one year of postoperative prophylactic drug therapy after intestinal resection in Crohn’s patients: Results of the APPRECIA trial Digestive And Liver Disease. 20194: 535-529 FI: FI:3,57(Q2)
  8. Shen, Bo, Kochhar, Gursimran, Navaneethan, Udayakumar, Liu, Xiuli, Farraye, Francis A, GONZALEZ LAMA, YAGO, Bruining, David, Pardi, Darrell S, Lukas, Martin, Bortlik, Martin, Wu, Kaicun, Sood, Ajit, Schwartz, David A, Sandborn, William J, Global Interventional Inflammatory Bowel Disease Group, Charles, Roger, Chen, Yan, González Suárez, Maria Begoña, Iaccuci, Marietta, Kabayashi, Tako, Kotze, Paulo, Lan, Nan, Li, Yue, Mao, RenRole of interventional inflammatory bowel disease in the era of biologic therapy: a position statement from the Global Interventional IBD Group. Gastrointestinal Endoscopy. 20192: 237-215 FI: FI:6,89(Q1)
  9. Chaparro, Maria, Garre, Ana, Ricart, Elena, Iglesias-Flores, Eva, Taxonera, Carlos, Manosa, Miriam, VERA MENDOZA, MARIA ISABEL, Minguez, Miguel, Arguelles, Federico, de Castro Parga, Luisa, Arroyo, Maite, Lopez-Sanroman, Antonio, Rivero Tirado, Montserrat, Guardiola, Jordi, Martin Arranz, Maria Dolores, Beltran, Belen, Barrio, Jesus, Riestra, Sabino, Garcia-Planella, Esther, Calvet, Xavier, Alcain, Guillermo, Sicilia, Beatriz, Garcia, Santiago, Esteve, Maria, Marquez, Lucia, Fernandez Salazar, Luis Ignacio, Gutierrez Casbas, Ana, Piqueras, Marta, Bermejo, Fernando, Perez Calle, Jose Lazaro, Hinojosa, Joaquin, Rodriguez Perez, Antonio, Aldeguer, Xavier, Garcia Sepulcre, Mariana Fe, Bujanda, Luis, Martinez Montiel, Pilar, Lorente Poyatos, Rufo, Rodriguez Gutierrez, Cristina, Merino, Olga, Lu. et alDifferences between childhood- and adulthood-onset inflammatory bowel disease: the CAROUSEL study from GETECCU Alimentary Pharmacology & Therapeutics. 20194: 428-419 FI: FI:7,515(Q1)
  10. Calvet, Xavier, Saldaña, Roberto, Carpio, Daniel, Mínguez, Miguel, VERA MENDOZA, MARIA ISABEL, Juliá, Berta, Marín, Laura, Casellas, FransescImproving Quality of Care in Inflammatory Bowel Disease Through Patients’ Eyes: IQCARO Project. Inflammatory Bowel Diseases. 2019: – FI: FI:4,261(Q2)
  11. Chaparro, Maria, Aterido, Adria, Guerra, Ivan, Iborra, Marisa, Luis Cabriada, Jose, Bujanda, Luis, Taxonera, Carlos, Garcia-Sanchez, Valle, Marin-Jimenez, Ignacio, Barreiro-de Acosta, Manuel, VERA MENDOZA, MARIA ISABEL, Dolores Martin-Arranz, Maria, Hernandez-Breijo, Borja, Mesonero, Francisco, Sempere, Laura, Gomollon, Fernando, Hinojosa, Joaquin, Bermejo, Fernando, Beltran, Belen, Rodriguez-Pescador, Ainhoa, Maria Banales, Jesus, Olivares, David, Aguilar-Melero, Patricia, Menchen, Luis, Ferreiro-Iglesias, Rocio, Blazquez Gomez, Isabel, Benitez Garcia, Beatriz, Guijarro, Luis G., Marin, Alicia C., Bernardo, David, Marsal, Sara, Julia, Antonio, Gisbert, Javier P., PREDICROHN Study Grp GETECCUFunctional rare variants influence the clinical response to anti-TNF therapy in Crohn’s disease Therapeutic Advances in Gastroenterology. 2019: – FI: FI:3,52(Q2)
  12. SUAREZ FERRER, CRISTINA JULIA, GONZALEZ LAMA, YAGO, González-Partida, Irene, CALVO MOYA, MARTA ISABEL, VERA MENDOZA, MARIA ISABEL, MATALLANA ROYO, VIRGINIA, Arevalo Serrano, Juan, ABREU GARCIA, LUIS ESTEBANUsefulness of Thiopurine Monotherapy for Crohn’s Disease in the Era of Biologics: A Long-Term Single-Center Experience. Digestive Diseases And Sciences. 20193: 879-875 FI: FI:2,751(Q3)
  13. Canete, Fiorella, Manosa, Miriam, Casanova, Maria Jose, Gonzalez-Sueyro, Ramiro C., Barrio, Jesus, Bermejo, Fernando, Nos, Pilar, Iglesias-Flores, Eva, Garcia-Planella, Esther, Lazaro Perez-Calle, Jose, Vicente, Raquel, VERA MENDOZA, MARIA ISABEL, Ramos, Laura, Rivero, Montserrat, De Francisco, Ruth, Montserrat, Antonia, Benitez, Olga, Navarro, Pablo, Taxonera, Carlos, Hinojosa, Esther, Marquez-Mosquera, Lucia, Navarro-Llavat, Merce, Ramirez-de La Piscina, Patricia, Gomollon, Fernando, Rodriguez-Alonso, Lorena, Nunez-Alonso, Alejandro, Fernandez-Salazar, Luis, Almela, Pedro, Rios Leon, Raquel, De Castro, Luisa, Gisbert, Javier P., Ricart, Elena, Cabre, Eduard, Domenech, EugeniAdalimumab or Infliximab for the Prevention of Early Postoperative Recurrence of Crohn Disease: Results From the ENEIDA Registry Inflammatory Bowel Diseases. 201911: 1870-1862 FI: FI:4,261(Q2)
  14. Sicilia Aladren, Beatriz, GONZALEZ LAMA, YAGO, Garcia-Alvarado, Maria, Sierra, Monica, Andres Barrio, Jesus, Prieto Vicente, Vanesa, Hernandez, Luis, Velayos, Benito, Arias Garcia, Lara, RELEA PEREZ, LUCIA, Suarez, Patricia, Atienza, Ramon, Vasquez, Monica, Fernandez-Salazar, Luis, Munoz, Fernando, GEICYL Grp Inflammatory Bowel DisEven non-experts identify non-dysplastic lesions in inflammatory bowel disease via chromoendoscopy: results of a screening program in real-life Endoscopy International Open. 20196: 750-743 FI: FI:0(Q)
  15. Sturm, Andreas, Maaser, Christian, Calabrese, Emma, Annese, Vito, Fiorino, Gionata, Kucharzik, Torsten, Vavricka, Stephan R, Verstockt, Bram, van Rheenen, Patrick, Tolan, Damian, Taylor, Stuart A, Rimola, Jordi, Rieder, Florian, Limdi, Jimmy K, Laghi, Andrea, Krustinš, Eduards, Kotze, Paulo G, Kopylov, Uri, Katsanos, Konstantinos, Halligan, Steve, Gordon, Hannah, GONZALEZ LAMA, YAGO, Ellul, Pierre, Eliakim, Rami, Castiglione, Fabiana, Burisch, Johan, Borralho Nunes, Paula, Bettenworth, Dominik, Baumgart, Daniel C, Stoker, Jaap, European Crohn’s and Colitis Organisation [ECCO], European Society of Gastrointestinal and Abdominal Radiology [ESGAR]ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 2: IBD scores and general principles and technical aspects Journal Of Crohns & Colitis. 20193: 273-273 FI: FI:8,658(Q1)
  16. Maaser, Christian, Sturm, Andreas, Vavricka, Stephan R, Kucharzik, Torsten, Fiorino, Gionata, Annese, Vito, Calabrese, Emma, Baumgart, Daniel C, Bettenworth, Dominik, Borralho Nunes, Paula, Burisch, Johan, Castiglione, Fabiana, Eliakim, Rami, Ellul, Pierre, GONZALEZ LAMA, YAGO, Gordon, Hannah, Halligan, Steve, Katsanos, Konstantinos, Kopylov, Uri, Kotze, Paulo G, Krustinš, Eduards, Laghi, Andrea, Limdi, Jimmy K, Rieder, Florian, Rimola, Jordi, Taylor, Stuart A, Tolan, Damian, van Rheenen, Patrick, Verstockt, Bram, Stoker, Jaap, European Crohn’s and Colitis Organisation [ECCO], European Society of Gastrointestinal and Abdominal Radiology [ESGAR]ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications Journal Of Crohns & Colitis. 20192: 144-144 FI: FI:8,658(Q1)
  17. Eliadou, Elena, Moleiro, Joana, Ribaldone, Davide Giuseppe, Astegiano, Marco, Rothfuss, Katja, Taxonera, Carlos, Ghalim, Fahd, Carbonnel, Franck, Verstockt, Bram, Festa, Stefano, Maia, Luís, Berrozpe, Ana, Zagorowicz, Edyta, Savarino, Edoardo, Ellul, Pierre, Vavricka, Stephan R, CALVO MOYA, MARTA ISABEL, Koutroubakis, Ioannis, Hoentjen, Frank, Luis, Fernández Salazar, Callela, Francesca, Cañete Pizarro, Fiorella, Soufleris, Konstantinos, Sonnenberg, Elena, Cavicchi, Maryan, Wypych, Joanna, Hommel, Christophe, Ghiani, Alessandro, Fiorino, Gionata, ECCO CONFER COMMITTEEInterstitial and Granulomatous lung disease in inflammatory bowel disease patients. Journal Of Crohns & Colitis. 2019: – FI: FI:8,658(Q1)